As a datapoint of one, I've been using Void Linux for near a decade.
I haven't once been in a situation where I thought systemd would help. Granted, I don't run many custom services, but for what it does, runit does a great job. Something a bit more user friendly like s6 would be nice, but otherwise it stays out of my way and I don't think about it.
NixOS/Guix would be worthwhile switching to, but Void is comfortably simple.