A simple example might be simply starting and closing the engine after the automated build & package process to make sure the game actually runs, but I've seen things like using bots to emulate player behaviour to smoke test gameplay functionality. No Man's Sky used automated tools to evaluate the procedural-generation algorithms[1]. Here's a more comprehensive example of automated gameplay testing[2].
[1] https://youtu.be/sCRzxEEcO2Y?t=3100 [2] https://www.youtube.com/watch?v=VVq_hgaX8MQ