Drugs aren't magical life-ruiners, that suddenly descend on unsuspecting healthy people and destroy them. The people you're describing are mostly already damaged by their own lives, hurting badly, and unable to emotionally function on their own. If you removed heroin or meth from the equation, they'd get drunk, instead... And they'd be roughly the same blight on their surroundings, regardless of their choice of substance.

Our drug problems are, at root, a mental health issue. And neither will ever be resolved in a society that doesn't understand that both problems are one.

If you are saying addicts commit crimes e.g. burglary well then prosecute them for those crimes, that’s the only way I can take the “blight on their surroundings. Taken a different way, there are a lot of humans in the us who use other drugs, alcohol e.g. who are not considered a blight on their surroundings. Street drugs could be like those drug, and in fact during prohibition alcohol was an illegal “street” drug.

Prosecute the addicts for the crimes they commit instead of criminalizing addiction.