This still sounds like precisely what I described. Euler's three-body problem is two fixed point masses, so there's no relative motion by construction, and the restricted three-body problem in a rotating/pulsating reference frame has mathematical transformations applied so the two bodies are "effectively fixed" relative to each other in that reference frame (while preserving effects due to rotations, such as centripetal/centrifugal forces).

The question in such a case becomes whether such a thing is substantially better than a regular n-body integrator. Euler's three-body problem may lose some useful n-body effects such as Lagrange points, which partially defeats the purpose of moving away from Keplerian orbits, and the restricted three-body problem arguably isn't simplified enough compared to full-blown n-body integration to be worth it.

> I'll rephrase. The gravitational vector on the craft won't be shifting very fast, so you can get away with a quite big timestep.

Ah, that makes more sense. IIRC Principia has an adaptive timestep, so it already does that, though that's with full n-body calculations. Swapping between the approximation and proper n-body depending on position relative to other bodies seems like a rather complex scheme, though, and I'm not sure whether that'd be the best approach.