They try to restrict you from using consumer cards for HPC computing and have it in their EULA. You can circumvent it a bit, but if you want to buy a hardware compute cluster you _can_ have problems if you want to use consumer grade cards (many hardware vendors that sell clusters kind of ignore this though)
Also nvidia just released (and did something like this before) GPUs specifically for miners. This was seen critical for many reasons for instance the fact that it was done while a "silicon shortage" was/is happening and the inability for users to later use these cards for gaming (note: nvidia fucked up royally and released a driver that can circumvent those restrictions)
Those are just a few examples.