Within reason, I personally am not offended by small variations based on legitimate negotiating for larger volumes (or even smaller volumes). I feel like most places will give you at least a bit of a discount if you offer something in return like enough volume to make it less hassle to sell to you.
Or if you just ask... I've definitely gotten 5-10% "discounts" multiple times just by asking if they can give me one. I figure this is the "wasn't price sensitive enough to ask" surcharge.
But if the prices were super random feeling yeah, for sure. I haven't personally run into more than a ~5-10% variation myself usually.
I think the only time I hear about it is when I get a price from a vendor, turn them down, and then have them come back with an offer for the same thing at 25% off. At that point they're kind of highlighting that their pricing is 25% higher than it needs to be for them to make a healthy profit so while I might take them up on it (once) I'm extremely likely to find a new vendor.
I've definitely done that before with a company that had dramatically overpriced high speed cameras. We kept ordering from them because we didn't want to worry about changing the brand. I doubt we'll order from them again.