The ship/mind Grey Area is explicitly condemend and ostracised from polite society because of it, for example.

(The simulation problem: If you want to simulate a society of sentient beings to figure out what they would do, then your simulated entities also have to be sentient for your simulation to be 100% accurate, but then you've accidentally created sentient life, which has rights, so shutting down your simulation is genocide, which means you now have to commit to keeping that simulation running for eternity, which is too much of a bother so you shouldn't do it in the first place.)