My company uses it and tolerates it, but at this point it now takes 8-10s to load a single issue from the board view, and ~5s to toggle the edit state. There is basically not a single action I can perform that takes less than 5s to execute, and some take more (backlog, etc. view take upwards of 30s to load a few hundred issues).
This is just not OK. And we're using hosted, Next-Gen. No fancy customizations.
Every. Single. Click. takes 5s+ to register a reaction. I'm on a gigabit internet connection and have a 16" MacBook Pro with all the dials turned up (eg it is NOT me).