IME (admittedly in a different context, doing UI development) Clojure's seqs and other immutable data can be a huge performance drag due to additional allocations needed. If you're in a hot loop where you're creating and realizing a sequence immediately, it's probably much faster to bang on a transient vector. Same with creating a bunch of immutable hash maps that you then throw away; better to create a simpler data structure (e.g. a POJO or Map) which doesn't handle complicated structural sharing patterns if it's just going to be thrown away.
Transducer's would help in the author's first case to take the map/filter piped through the `->>`, which is going to do two separate passes and realize two seqs, and combine it into one.