I happen to work for the man and here are some issues. I can't release code as open source, I get paid the same regardless of whether I work my ass off or just do enough to be ahead of the curve, I have virtually no say in our products because I'm just an engineer (we have product people for product design), I have to get an act of congress passed to setup a server in a non company standard configuration, etc, etc, etc.
There are some up sides, one is that I get to focus and think deeply about my specific problem space which at one time was search relevance, and is now data mining. I don't have to do sys admin work, even though sometimes I'd rather do it, I have access to a very large hadoop grid that non startup would have built prior to success, there are a lot of really smart people with diverse backgrounds to bounce ideas off of, etc, etc.
Oh, but this man I work on is focused on ad clicks :)