Scheme is opinionated and wants you to program in a certain way (hence TCO being part of the standard), it's also more static and doesn't want to take over the whole machine like Common Lisp and Smalltalk want.

I started with Scheme but I am no longer my idealistic self so I am partial to Common Lisp since I use it for work and don't mind coding in ugly kitchen sink languages as long as they are fit for production use. Not that Scheme lacks amazing implementations such as Chez, Gambit or Chicken (my favourite) but I would have a harder time building something non trivial in those.

As a counter argument you have https://fare.livejournal.com/188429.html from a seasoned Lisper so YMMV.