Sure, but you take a massive performance dive marshalling things through Python. Additionally the Python API is only semi stable between releases.

If you want to add performent extensions to Blender, it requires maintaining an entire fork of the app.

Contrast this to other DCCs, where they almost all provide compiled plugin support (usually C++) and API stability is largely guaranteed between releases.

This makes Blender very unfriendly for production pipelines.

Add to that, Blenders Python extensions don't have a very friendly UI story via ghost, whereas other DCCs largely provide a Qt + PySide2 backing.

Fwiw I'm very much pro blender, having rolled it out to artists in production settings, but I am far from recommending it in any core production pipelines unless the studios are willing to maintain an entire fork of the app.