Especially the "recovery" one, praised by everybody where the inclusion criteria was: "having flu like symptoms", without PCR. This is true science indeed.
https://www.les-crises.fr/the-tremendous-ethical-and-methodo...
1. Why is this a major flaw?
2. As stated by the title.
Remark: (Well conducted) RCTs introduce way too much variance.
As a statistician I care about a good trade-off between bias and variance.
OTOH, you don't need RCTs when you measure a physical property of a system.
3-6,8. Valid points. Especially as of publication date.
As of today, they updated the study with 3000+ patients.
7. This is not ethical.
9. Object of the study: measure viral load. After the cytokine storm, you don't care much about the virus.
10. We should ask DR directly about it, this is grave.
11-13. Irrelevant. They did PCRs to everyone, the important measure is the CT.
14. This is not good indeed.
15. PCR tests are reliable.
16. Why is it a flaw?
17-18. They published a lot of other papers on their work, and updated the early study.
