Just for balance, I use KDE Plasma with an AMD graphics card but almost no games work, even those with a "gold" rating on ProtonDB.
I haven't had time to Google how to debug the problem, but only about 1 in 10 games "just work"
Update: OK, instead of surfing HN I googled the problem. I think it may be that my games are installed on an NTFS drive. I will try moving the installs to a new drive and see if I have more success!