I've never taken LSD, nor to I plan to, but every, EVERY, person I've talked to that have, talk about how it changed thier lives dramatically.
It seems there are a fair ammount of people on here somewhat scared of the way drugs alter you, (hey, this is hacker news, why not hack yourself? you only live once, see what happens) but it's really one of those things you will never understand until you experience for yourself.