General artificial intelligence, once we figure it out, will cause an increase in the annual economic growth more extreme than even the industrial revolution caused. Either that or a disaster, but hopefully the former.

Anyone who thinks we will run out of things to create just lacks imagination. There's so much stuff we'd really, really like to have but haven't been able to economically create yet. Medicine, body modifications, automation of all that's boring, cheaper manufacturing of everything, entertainment, recreation, transport, space habitats and almost anything else you can imagine.