It's hard to find a full size bluetooth keyboard. I think I went through every keyboard on Amazon and found only one. If you use a USB wireless keyboard, well, there goes one of the two USB slots on the laptop.

It's not just the monitor being big, I want lots and lots of pixels. I'm currently running 3840*2160, and have a second monitor attached set up in portrait mode (so I can display a manual page while I work on the other one).

Of course, I'd get an even bigger monitor with more pixels if they didn't cost so dang much :-) How big, you ask? A wall size retina display! I've wanted one for 40 years.

Agreed. I spent 18 years working primarily on a laptop, and was happy with it. But then I gradually switched to a desktop for the last 7 year with tons of screen space (46" 4K plus 2 24" "wing" monitors. But for the last 6 months I've been working at home, and having my primary machine be able to move to and from the office easily, sounds pretty good what with the pandemic situation.

My setup now is a laptop with the USB-C docking station. So I plug in one USB-C cable and get:

30" external display, ErgoDox Ez, USB mouse, bigger speakers, 120W power, Mic for zoom calls.

That just sounds like a desktop with extra steps.