Which compiled language adds 680564733841876926926749214863536422912 and 35370553733215749514562618584237555997034634776827523327290883 in one instruction?

FWIW, here's the relevant dispatch code in Python's ceval.c where you see it uses a very generic dispatching at that level, which eventually, deeper down, gets down to the "oh, it's an integer!"

        case TARGET(BINARY_ADD): {
            PyObject *right = POP();
            PyObject *left = TOP();
            PyObject *sum;
            /* NOTE(haypo): Please don't try to micro-optimize int+int on
               CPython using bytecode, it is simply worthless.
               See http://bugs.python.org/issue21955 and
               http://bugs.python.org/issue10044 for the discussion. In short,
               no patch shown any impact on a realistic benchmark, only a minor
               speedup on microbenchmarks. */
            if (PyUnicode_CheckExact(left) &&
                     PyUnicode_CheckExact(right)) {
                sum = unicode_concatenate(tstate, left, right, f, next_instr);
                /* unicode_concatenate consumed the ref to left */
            }
            else {
                sum = PyNumber_Add(left, right);
                Py_DECREF(left);
            }
            Py_DECREF(right);
            SET_TOP(sum);
            if (sum == NULL)
                goto error;
            DISPATCH();
        }

Python code can be made more high performance if there's some way to tell the implementation the types, either explicitly or by inference or tracing. That's how several of those listed projects get their performance.