I think the reason that HN, Reddit et al. have this impression is that state policies in conservative states are explicitly less restrictive than those in less conservative states. Florida just removed all stadium event attendance limits, for example. Within any given state there are all kinds of political beliefs and economic situations that may be more or less correlated with spread, but state governance is a very big variable.

Anecdotally, out here in the rural wilds of Alabama, most people seem to be wearing masks. I recently went into downtown Huntsville and no one was. Poverty and essential workers may be a significant component, but given the behavior of the young and affluent here, I don't think that is all of it.

Yes, you'd say that the Red areas are on aggregate older, poorer and less likely to work from home.

That said, at my regional college in the Deep South, case numbers have dropped noticeably since the beginning of term - instead of 30 cases every day we have now ten, and there have been remarkably few outbreaks at frathouses, all that despite no organized testing.

Conservative people are much more likely to live in rural areas. Liberals in more urban areas. Viruses spread much more effectively in higher population densities.

So you'd really need to look at per capita infection rates and control for density, not absolute numbers.

For some anecdata, in my moderate county we have a mask mandate. The surrounding less populated and much more conservative areas don't. Since the mask mandate was put in place more than half of the cases in my county's hospitals have been from the surrounding counties. Despite that fact that they have an order of magnitude fewer people, and despite that fact that we have far more people living in poverty in absolute terms than they do.