The issue with Discord is if the message compose box is focused the cursor keeps flashing and redrawing a big tile of the screen even in the background, manually defocusing the message box fixes this. This is also something Discord could easily fix I think.
…if they knew about or cared, which I suspect they certainly didn't until now. Based on the number of things on my screen that force 60 FPS drawing, there's many developers who never notice :(