What doesn’t always work for me is the physical detritus after a work period - notes, papers, books etc. and even more so, the psychological carry over from difficult or prolonged periods of work.
I find that if I work 10 hours a day (common) during the work week, for weeks at a time, if I take a break, it will take a minimum of 3-5 days with lots of naps/downtime to process the “work carryover effect” and return to a state where I can truly think about what I personally want to.
Anybody else?