JSONB columns are incredibly useful if you have data that doesn't fit well into a strict relational schema. And they are very powerful in terms of query ability in Postgres, but still quite far from a conventional relational schema.
Queries that act on the insides of a JSONB column are much harder to write than the equivalent conventional queries. They are also much, much slower in certain cases as the DB has to read the entire JSONB blob in many cases, and because they don't have proper statistics. The performance can range from slightly slower to completely pathological query plans that take ages.
I'm a big fan of JSONB in Postgres, but it is no replacement for a relational schema, there are far too many problems you inflict on yourself if you try to use it like that.