You press the key on or close to the the near edge using your thumb either way, so it really doesn't matter.
(This comment typed on an Ergodash: https://github.com/omkbd/ErgoDash It would be possible to press the key labelled with the noodle bowl using my thumb, although I'm not in the habit of doing so. I might try and make it a habit, now I think about it. The top half of the "Enter" on the right side is pointless; my keyboard has 2 small keys instead of the large one.)
