100,000 hands is nothing. Ask any long time pro who understands the game. I've personally known several who play a very consistent, disciplined style against a consistent level of opponents whose results would vary greatly across 100k hand sets, from being a huge winner to barely breaking even to losing even though they all were at least steady winners overall.
When you get in the 500k+ realm, it starts to get more reliable, but even streaks of this size are possible at the statistical fringes.