Here's a sample workflow: I'm hacking on some code in /home/john/foo. I have a directory window open in /home/john/foo, plus the files foo.go and foo_test.go open. I make some changes in foo.go, then in the directory window I type `go test`, select it with the mouse, and middle-click. This runs `go test`, creating an "Errors" output frame in the rightmost column. If the tests pass, this frame just says "PASS". If the tests fail, it'll say something like `./foo.go:27:10: undefined: xyz`. I right-click on `./foo.go:27:10` and Acme immediately takes me to that like in the appropriate file. I make a change, execute "Put", and then middle-click `go test` again to try the tests once more.
The delve debugger also prints line numbers that work with Acme. I run delve in an Acme terminal, and when I e.g. print a backtrace, I can simply right-click any of the line numbers to jump immediately to that code (Acme will open the file in question if it's not already open).
acmego will run gofmt and automatically add/remove imports as necessary every time you save the file, which is a huge convenience.
There's no syntax highlighting, which is a huge dealbreaker for some people. Personally, I find it distracting to watch huge swathes of my file change colors because I typed ", then change back as soon as I close with another ", so the lack of highlighting is great for me.
Edit: in my sample workflow above, I mentioned typing `go test` right in the directory window, but that's just ephemeral... you'll lose the commands if you refresh the file list, etc. A more permanent thing is to drop useful commands into a "guide" file in that directory; that way you can keep a whole suite of commands to run tests, run benchmarks, build & deploy, etc. right at your fingertips.
Edit 2: There's also a number of Language Server Protocol clients for Acme (see https://news.ycombinator.com/item?id=23782439 and https://github.com/fhs/acme-lsp) but I don't use them... I'm old-fashioned.