If you're an employee, it's irrelevant.
If you're self employed, the mental overhead and switching costs are high.
And if you are the person for which those things are true, do you believe the marketing?
Wouldn't 5 minutes memorizing keyboard shortcuts be a better use of time, at $0/monthly cost?
I would argue that the area in which people fail to consider the value of time is actually the time cost of implementing new processes, software or otherwise.
There are hundreds of thousands of free courses and tutorials that could each save someone a little here and a little there, why doesn't everyone spend all day learning?
It's an interesting question, really.
I lean towards pick the 2-3 core activities and optimize for time and output with those tools. For everything else, optimize for low mental overhead.