>Does it really handle everything?
It does for my use case, but obvious your mileage may vary.
>Can I turn of part of the screen, if I actually only need smaller space?
Sort of. The monitor can split into dual source mode that has two 1920 sources side by side. You could potentially turn that on and set one side to an empty source. You can also always use a black desktop if you need the rest of the monitor to be dark to allow you to focus on whatever window you have open.
>Can I position a 1920 default width space right in the middle in front of me without it looking weird (i.e. symmetry of screen hardware borders)?
How do you accomplish this with two monitors currently? You would have to choose between symmetry or having one monitor front and center. The Dell software allows you to customize the drag and drop regions. I use three columns that are the full height of the screen. You could set it up to have a 1920 section in the middle with two 960 columns on each side. You could also setup your physical workspace so one side of the monitor is centered in your vision instead of the center of the monitor. Also I have mine mounted on a monitor arm that allows me to reposition it as needed.
> Are workspaces working correctly (in unix, windows, macos, all of them?)
It works in Windows and that is the only native GUI I use. Everything obviously works fine when in the terminal and I rarely increase the resolution of a VM past 1920. I would frankly be shocked if there wasn't similar software available for Linux and OSX that allowed you to setup customized zones like Dell's software if you need to run one of those natively.