Must look into GraalVM at some point, but, as someone new to Clojure, I'm wary of spending too much time on tooling yet. I've found in the past I can tinker so much with such things that it interferes with getting fluent with more fundamental stuff.

I'd be interested to see if either now or in the future Clojure + JavaFX in GraalVM would be feasible.

Edit: I don't quite get the install size issue - I thought native image was an entirely standalone executable?