Yes.
Anyone that hasn't been exclusively using macOS for their entire digital life, or at least years, anyway.
'Command' (resp. 'Windows', resp. 'Super') is a different story. You can't say 'Super' with a straight face without also marking yourself out as someone who borders on saying 'GNU with Linux', or 'I run Arch'.
(For what it's worth, I do run Arch. ;))
IIRC Option is dually labelled as Alt on some Apple keyboards anyway.