Impact meaning my impact on the product, not my impact on humanity as a whole. I get more satisfaction from a larger impact on a product that affects less people than less impact on a product that affects many more people.

I guess I'd rather be the town baker than work at Wonder-Bread.

One way of looking at it is your_impact = your_contribution * number_of_users. If you work for a mega corp chances are your contribution is small so you would be better off in a small(er) company.

The more I work as a programmer the more I agree with points 1 and 2. With Coronavirus I'm having the change to work remote 100% of the time and I'm enjoying so far. It's likely that's something I'm going to pursue in the future.

For me nothing beats the feeling I get when I read a heartfelt message from a user who's happy about something I decided / did personally.