I've personally found the entire industry off putting at how much it's about prestige and how specific collectors see an artist or a piece.
But at the same time, I don't think normal people want to pay high prices for art. It just doesn't serve much value to them. If your users haven't heard of Saatchi or Artsy, what are they doing buying art and why do you think this is going to be a large market?
It seems like you'll end up with low priced artwork and artists who want to graduate to a "real gallery" when they get bigger, and so you really need volume to make to work. Respect the hustle from one YC founder to another but scratching my head on this one.