When I went out for groceries this week (weekday late evening to avoid crowding) I was the only one in the store wearing a mask. Rationally I knew it was reducing risk for others but I still felt deeply uncomfortable being the odd one out.
Contrast this with places like Taiwan where a mask isn’t considered abnormal, and becomes a matter of course during times like this.
Catching a Corina virus with less than 15 minutes personal contact is very unlikely and it's extraordinary unlikely to be able to acquire a virion and get it to a host cell just walking past an infected perso on the street.
It's not even clear how infectious the surface to face vector is.
Italians and Spaniards running around kissing each other and rubbing cheeks as is their ancient custom likely has more to do with the issues there than anything
Masks are very hard to come by... that might be why it looks like business as usual? I'd love to get some myself, tips appreciated.
It's literally not okay to be wearing gloves in a chemistry/biochemistry building when you push an elevator button.
My daughter is also sewing cloth mask using a pattern from https://www.craftpassion.com/face-mask-sewing-pattern/
I know these aren't as good, but they probably improve my chances of avoiding SARS-CoV-2 by at least 10% when I have to go outside. I plan on using them once, then leaving them in a bucket in the garage. Once I've used them all up, I'll wash them and by that time (and hopefully the detergent + bleach action), the virus will be dead.
Several states fairly recently passed laws requiring food preparers to wear gloves. Then they backtracked when they realized that they actually decreased safety.
For the average person, a mask likely is an individual benefit. But in a world with insufficient masks and asymmetric risks, social benefit, literally the health of the public, benefits most by limited and targeted use.
Distinguishing between personal and communal risk is critical here. That message has been poorly conveyed, even by ordinarily excellent communicators -- Zynep Tufekci comes to mind.
My comment was in the context of "what can time fix", which would mean supplying healthcare workers and everybody else with masks before letting up. Retail workers wearing masks would go a long way to creating some peer pressure to act differently.
From what I understand the best prevention is to reduce face-to-face contact with other people where possible, but an N95 mask would definitely help prevent contraction in public spaces.
Of course, these measures seem extreme since ~80% of people will barely notice they are infected / have mild symptoms, but it's all about peak-load reduction.
[1]: https://www.youtube.com/watch?v=V1xBiBVH7U4 [2]: https://www.youtube.com/watch?v=E3URhJx0NSw&t=7s
It gives you very limited protection. There's no replacement for just avoiding people, 15 feet away from everyone.
They're mainly good for people who are infected to not transmit pathogens.
When doctors operate on infectious people, they wear hazmat suits. Full face mask, air filter and body condom. You can get a virus through your ears, eyes, mouth, nose, or microabrasions on your skin.
You can wear a mask, but I fear that people will start thinking it's anywhere near full protection. False sense of security is probably not worth even encouraging in a situation this dire.
Worse yet is that if we let the measures off, we just get the same curve later. A bit lower at peak, but still exceeding healthcare capacity several times (say, 6x rather than 8x, if we do a 5-month lockdown).
But this still saves lives - just not anywhere as many as we could have saved if we contained it. It also gives us a chance to build more hospitals, manufacture more ventilators etc - although it still won't catch up with demand.
The best endgame is that we either get a vaccine, or enough tests to test everybody, and then do targeted quarantine from there.
Also locking down everything DOES stop the exponential spread. That's the whole point. If you don't see other people, you aren't spreading the disease, reducing the rate of new infections. If each infected person infects less than 1 other person on average, we'll have stopped the spread. China and SK have already succeeded in this.
- Gilead Sciences; remdesivir for treatment; currently in phase 3 clinical trials
- Ascletis Pharma; danoprevir/ritonavir for treatment; currently in phase 1 clinical trials
- Moderna Therapeutics; mRNA vaccine; currently in phase 1 clinical trials
- CanSino Biologics; attenuated vaccine; currently in phase 1 clinical trials
- Arcturus Therapeutics; hybrid RNA vaccine; currently preclinical
- BioNTech; mRNA vaccine; currently preclinical
- CureVac; mRNA vaccine; currently preclinical
- Eli Lilly; isolated antibody treatment; currently preclinical
- GlaxoSmithKline; vaccine adjuvants; currently preclinical
- Inovio Pharmaceuticals; DNA-based vaccine; currently preclinical
- Johnson & Johnson; attenuated vaccine; currently preclinical
- Pfizer; assistance with both vaccines and treatments
- Regeneron Pharmaceuticals; engineered antibody treatment; currently preclinical
- Sanofi; hybrid DNA-based attentuated virus vaccine; currently preclinical
- Takeda; isolated antibody treatment; currently preclinical
- Vir Biotechnology; isolated antibody treatment; currently preclinical
Most of these are in very early stages, but I'm optimistic that that speed of development of both treatments and vaccines will exceed the consensus expectations.
This, along with recent advancements in bioengineering will, I believe, lead to surprisingly rapid progress.
(The best current mouse models for human coronavirus are not very good; the mice are generally resistant to the virus, so it's difficult to determine whether a vaccine or treatment is working.)