- ability to plug into any monitor at any resolution that monitor supports

- ability to copy and paste to/from my phone

- Transmit - I really haven't found many good s3 clients on Linux

- ScreenFlow

- Git Tower

Most of these have some sort of a work-around or close analog of course. (So I'd likely not be "giving anything up" as much as compromising or learning new techniques) However, I'm not sold on the benefits (other than ideological ones, the only thing that comes to mind is increased Docker performance) outweighing the costs. For someone with a different workflow and set of tools, a different conclusion may result.