It's non-startups that are having the hardest time finding talent thanks to tech giants (also not startups) getting into bidding wars over talent. Startups are in general fine -- they can sell the "upside" that more established companies can't. And non-profits might be fine too; I don't have much exposure there. But in my experience your average smallish public company has, over the past five years, seen a dramatic drop in level of experience and candidate quality at various IT positions that they haven't experienced in other kinds of engineering roles, despite continuously ratcheting up salaries to compete. Smells a lot like the job market in 2008, right before a lot of talented people wound up unemployed.
In weakening financial markets (no matter the cause), companies often stop stockpiling talent and employees perceived as overpaid relative to their value (as valued by contribution to revenue) are often let go. There have been large layoffs in the past few weeks at LogMeIn, TripAdvisor and now Wayfair, but for now it's impossible to tell if it is a coincidence or a trend among Boston companies.