Re akuous and decibel, I don't know too much about their programs
Re eye diseases / blindness, there is at least one approved gene therapy for a form of congenital blindness, luxturna: https://www.fda.gov/news-events/press-announcements/fda-appr...
the eye is one of the areas where gene therapy delivery is currently feasible. other areas include the CNS using AAV9. Perhaps the most impactful gene tx yet approved is Avexis' Zolgensma (Avexis was acq by Novartis for $8-9B in 2018). Zolgensma is a potential cure for spinal muscular atrophy, the leading genetic cause of infant death. Zolgensma did $160M in its first full quarter on the market
Other areas where we will likely see approved gene therapies soon include blood diseases like hemophilia, beta thalessemia. In addition to blood, eye and motor neurons, the liver is a popular target for gene therapy as all of these tissues are easier to deliver gene tx to with current technology
Delivering gene tx to other tissues is not really feasible as far as i know at this point
