For context, I don't think anyone is suggesting that BTC's blocks would still be full if they were 100 times bigger, so it is premature to talk about competing with credit card processors.

However, 250 GB is approximately 25 GB per year (since Bitcoin started in 2009), which, if you multiply it by 100, is 2.5 TB per year. That means it will take about 6.4 years to fill a 16 TB hard drive, which should cost less than $600:

https://www.techradar.com/uk/news/worlds-largest-hard-disk-d...

It's not hard to imagine someone paying under $100 per year to run a full node, whereas on the day that TechRadar article was published, the average price of a bitcoin transaction was $4.58 as seen here:

https://bitinfocharts.com/comparison/bitcoin-transactionfees...