Fortunately, the loss of its empire is a process that always seems to leave the nation in question better off, at least in modern times. As I see it the only possible justification for total galactic conquest is self-defense: do unto others before they can do unto you, more or less as you put it. Any advanced civilization that doesn't see that as a self-defeating justification is so different from my way of thinking that I couldn't possibly deal with them on any terms, offensive or otherwise.
Basically, what you're saying is that the only way to survive and prosper in the Universe is to be a murderous, psychopathic douchebag on a galactic scale. Not down with that, sorry.