Lisp in general is not the epitome of simplicity. Lisp-2s like Common Lisp add some cognitive load for those used to simpler languages (although Lisp-2s have their advantages).
And of course, Lisps that include meta-object protocols (Flavours, Common Lisp again, &c.) deliver power, very elegantly, but for people unfamiliar with them, there is a learning curve to climb.