I would really like to give it a shot -- but for a couple thousand bucks for the initial series of treatments, I would hope that the change is more lasting.
Obviously everyone is different and YMMV, but for me- ketamine has been the only thing that made a real impact, bonus was the lack of nasty antidepressant side effects (I'm still taking an SSRI, SNRI, and a mood stabilizer and I hate them).
I'm hopeful that some of the new ketamine+___ compounds being created to extend the duration of the 'depression slightly lifted' feeling are successful and come to trial soon.
Combination of Wellbutrin & Dextromethorphan -- which is a dissociative with some side-effects similar to Ketamine. It's in trial for severe depression treatment. 15mg of DXM (which you can buy at any drug store) combined with 150mg Wellbutrin (which you can get your dr. to prescribe to you.) Could be worth a try...
- It doesn't necessarily hold for a few months. For some people, it's not too much longer than an infusion session; for others, they might not even need the "booster" infusions some get.
- There's some patients for whom the "tolerance" for the antidepressant effect doesn't go away even after O(years) without taking it when it initially worked and then stopped, so you can't necessarily just do it again. (Source for this one is that it happened to me, and did not return while going as high a dose as the doctor was comfortable with.)
For example, on Nov 27th, they wrote '[this year] I successfully treated depression with Ketamine'.
It's possible that they're not talking candidly on the shorter-form of an instagram post, but it's at least a sign that maybe it stuck, otherwise that phrasing would probably be a bit less positive.
If you don’t figure out how to give your life meaning, the drugs aren’t going to do it for you. They’ll give you time and space to do it, but you really need to make the best of the opportunity while you have it.
This guy’s blog post sounds exactly like a hundred conversations I had with people I met at raves. We all knew that it was making our lives better, but most of us were broken people going into the scene and at best a lot of us were slightly less broken coming out of it.
Someone I’m sure is going to say that it’s a medicine and not a party drug now because a nurse is giving it and someone wrote a prescription, but it’s the same drug with the same effect. I’m not saying that to be judge-y. I think people should have a right to improve themselves or have fun anyway they want to without hurting any body. Just that if this thing cured depression, there would have been a whole lot of ravers that were permanently cured and I know from personal experience that it isn’t the case.
I’d really hate to see people try this thinking they’re going to be happy and be even worse off after the fog settles in again.
These drugs, taken with a good group of people, always lead to a therapy-like experience. And as GP comment said, they give you the ability to clearly identify what bothers you in life and what to do about it. The only difference between 'medical' sessions and 'recreational' ones is that you're talking to a therapist instead of friends. Having done both, friends are generally the better option.
Actually acting on that information to improve your life is a completely different task, and without taking that step, these drugs do nothing for mental health long term.
There is no difference between 'medicine' and 'drug' other than some regulatory body slapping a label on it. Especially the case with psychedelics where early pioneers performed and documented way more experimentation than FDA-approved research could ever hope to cover.
Individuals reading this article from a purely logical, scientific materialist perspective, may form drastically different conclusions than those reading from the wide variety of different possible perspectives. And that's fine, it is the nature of humanity. But it seems very plausible to me that an inability (or unwillingness) of people to interpret ideas from multiple perspectives, is not fine.
There are many problems in the world (yes, I know, this has always been the case...from a binary perspective, but that is only one perspective on it). The world is complex, and getting more complex. Perhaps the manner in which we currently evaluate the world lacks the dimensional complexity required to manage it in a reasonably optimum way?
If(!) this was the case, what might that look like? What would discussions about reality look like? Is it possible that we might be in a situation similar to this? How might we know?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544340/
https://www.sciencedaily.com/releases/2016/03/160318090442.h...
https://www.nursingtimes.net/clinical-archive/medicine-manag...
Racemic was funny. Esketamine is extra-weird, I felt the movie on tv was real and I was chatting with Antonio Banderas, an undercover CIA operative. Later my body felt as a paper balloon. No K-hole though.
A year later: I haven't smoke weed since. I just got uninterested. No more ketamine, but I'm considering buying again. For months after the binge, alcohol didn't get me drunk, that was weird. Anxiety, a little better. Block was no better.
