I've been watching Lanyrd for a while now, and I think it has great potential. Anything that can bring some sort of order to the world of conferences would be a great thing - just ask any academic that needs to be on dozens of mailing lists to keep up with upcoming calls-for-papers. Also the social aspect could be great for networking.
It will, however, only be as useful as its coverage of conferences, so let's hope it gets adopted by conference organisers and attendees. Anyway, I wish them every success.