Mars is an inhospitable place, but technology allows us to live in inhospitable places.

In many ways, I expect Mars is like Antarctica. Once the initial romanticism of pioneering fades, it will have only very niche attractiveness for specific scientific causes. It used to be a popular idea that technological advancement would see us populating Antarctica and underground / undersea environments, yet despite that being possible with modern technology (e.g. nuclear powered greenhouses), we've not justified the endeavour.