Worst is certainly removal of 32-bit support. I'll personally never be using anything past Mojave. It would literally cost me from purchased software that is now incompatible and will not be updated.
To say Apple has lost its way would be an understatement. Apple is actively detrimenting those who have stayed in its ecosystem for decades. As a professional audio engineer, I refuse to lose several of my plugins to a quote-unquote 'upgrade.'
If I lose access to my software, you are not 'upgrading' my OS, you are removing access to what worked perfectly before.
I also refuse to lose Adobe CS6, by which I've paid a full license for. No, I have no interest in updates. I had no interest in updates post-CS3, to be honest.
There is no benefit to the lack of 32-bit support that could be worth losing it. If they did this because they're moving to ARM, fuck them. Don't let your behind the scenes process fuck with my day-to-day ability to work.
I'm literally going to have to leave behind my career as an iOS developer - I refuse by principle to purchase new Apple products ('vote with your money') - and I certainly refuse to accept an 'upgrade' that annihilates the usability of some of my most important software, in the name of...what? What possible benefit does removing 32-bit support lend to the customer? None. It's literally just a fuck you to me for supporting them for years. What a damn shame.