Depends on a few factors. Your home Country is one, if in the U.S. and the values are typically sized for credit cards, then use Stripe. Stripe is the easiest one to use, they are quick and things just work. Only time I've seen people complain about Stripe is when you are running a business that is in the no-no banking zone (e.g. porn etc).
I've personally used Stripe, and I've also done integrations with FirstData directly amongst some others. Stripe is easy and quick, and you can get better than 2.9% with them if your volume picks up.
If you are in the Enterprise range of pricing, e.g. 10's of thousands of dollars per client per month than you typically want to invoice and be paid via ACH/Wire.