Yea I wished it were easier to use out of the box too. The code is fortunately very well organized so you can just copy the pieces you need:
https://github.com/GoogleChromeLabs/squoosh/tree/master/src/...It also does make sense for you to pick and choose only the compression codecs you will need. Otherwise the cost of making every client download huge and unused wasm libraries might outweigh any bandwidth savings from compression.