Even if compression is the solution for most users, I would love to have a generator on the web site where I can click on "blue" and "orange" (because that's my color scheme and my site will never use teal), not click on "forms", "buttons" and "hover", and I get a quasi-minimal version of the CSS file.
My smallish sites don't use build pipelines and post-generators and so on, I'd just like a reasonably-sized CSS file to include.
(I realize that's a niche use of those frameworks)
Oh, and if I may dream, https://caniuse.com/#feat=css-apply-rule throughout all browsers would be great!