Have you every done anything entrepreneurial in healthcare or just tried to introduce a new or different treatment standard?

1) It just takes longer in this field. Takes longer, but not necessarily more difficult (technically).

It's a nightmare and when I helped consult to a couple teams for a bit I was shocked at the slow speed everything gets done at. Many reasons for that, but it's hard to describe how unlike a typical fast moving startup it is (unless your not changing patient protocols).

2) ML is moving faster than it was 10 year ago. Way faster. So comparing work done 20 years ago is difficult, they just didn't have the same resources, ecosystem, and momentum.

3) It's only a hard problem in practice not in principle and well suited to ML. Unlike some problems where difficulty in practice doesn't match difficulty in principle (like warp drive space travel), the remaining engineering and open research questions don't suggest anything that will hit a wall, or prevent ultimate success on the order of the time frame suggested.