The "Assange situation" is not complex, and it's not one-off. He published numerous secret documents that were deeply embarrassing to the governments of the United States, United Kingdom, and many other countries. He is being targeted for entirely political reasons, and the cooperation of the British and Ecuadorian authorities is likewise politically motivated. In the case of Britain, the motivation is twofold. Assange released documents about the UK government's actions, and the government wants to maintain good relations with the United States. In the case of Ecuador, the motivation is better relations with the United States and access to IMF loans.
The persecution of Assange is not one-off, because it sets a precedent for future prosecution of journalists in the United States, and it establishes that journalists are in danger in any country that has an extradition agreement with the United States.
Given all the concern about the Hong Kong extradition law being used to target critics of the Chinese government, I would expect the same people who oppose the HK law to also vigorously defend Julian Assange against extradition to the United States for political crimes.