On mine the plastic frame cracked between the power button and the volume control (I think a reasonably common problem with this phone, I've never had a frame crack on any other phone). After that one button gets stuck on, which makes phone cycle reboot - OK - I can workaround that. Then the microphone went bad: that is caused by the crack causing pressure on the micro-connector which causes an electrical issue. That wasted more time and eventually my workaround for that issue failed.
I have had close experience with 5 different Nexus devices, and 4 of the 5 had nasty failure modes.
The Nexus line has been far less reliable than the iOS devices I have had experience with, and all the Apple devices got far more security updates over their useful life. Note: I usually use Android phones and iPad tablets (although I have also personally had iPhones and Android tablets).
And then I heard the horror stories of everyone in my office who, having had a great experience with the N5, went and bought a Pixel.