No, it's not easy. I have a Flash based app I can't get out of using. Every day. Every day I have to tell Chrome to allow the app to run Flash. When I close the browser and reopen it, I need to tell tell Flash to "always" use Flash.
Chrome's definition of "always" is very different to everyone else's. And that's on purpose. But I have no say in what corporate app I can use, and I have no way of getting it migrated quickly. The Chrome devs seem actively hostile to the poor slob who must us the corporate app and have no way of migrating away from it.