The problem, as far as I understand it (though I’m a layman), is that by the time the dead code optimization pass runs, the code has been transformed so much that there’s no obvious way for the compiler to tell the difference between “obvious programmer-intended null check that we shouldn’t optimize out” and “spurious dead code introduced by macro expansion” or (in C++) “by template instantiation”.
Couldn't user defined branches be tagged by such a compiler and if a tagged branch is eliminated the error generated with a reference to the tagged line in question?